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In 2025, I’ve flown 82 flights—19 of those long-haul—across 12 airlines, spending a cumulative 16 days and 5 hours in the air. So yes, I know a thing or two about surviving a flight. From short hops to international hauls, economy seats to business cabins, frequent fliers know that comfort, preparedness, and a touch of strategy make all the difference between a smooth trip and a travel nightmare.
Over time, I’ve built a tried-and-true in-flight kit that helps me handle just about any issue that might arise at 35,000 feet—whether it’s a dead phone battery, an overzealous AC vent, or a sick neighbor. Below, I’ve rounded up 15 of my favorite Amazon finds that make never leave my personal item and make flying cleaner and far more comfortable—no matter where you’re headed.
Best Overall Travel Essentials
Clorox Disinfecting Wipes Pack of 3
Amazon
Planes aren’t exactly known for being the cleanest environments, which is why disinfecting wipes are a must. These Clorox wipes kill 99.9 percent of viruses and bacteria, and come in convenient, travel-ready packs that fit easily into a carry-on or personal item. Whether you’re wiping down your tray table, armrests, or even your phone after boarding, these pre-moistened wipes make it easy to keep your space (and your hands) a little more hygienic mid-flight.
Trendy Queen Women’s 2-piece Matching Set
Amazon
Your period comes. The plane is hot, and you sweat—a lot. Or worse, you miss a connection or your flight gets diverted, and your checked bag is halfway across the country. Having an extra set of clothes in your carry-on or personal item is a must, and this lightweight matching set makes it easy. Made from a soft, breathable cotton-blend fabric, it folds down super thin yet still feels cozy enough for lounging. The relaxed fit keeps you comfortable through delays or red-eyes, and the coordinated top and bottom mean you’ll still look put-together even when travel chaos hits.
Blissy Silk Sleep Mask
Amazon
For the red-eye that, for some reason, decides not to turn off all the lights, or when you’re seated just a little too close to the flight attendant station, an eye mask is a must. This one by Blissy is made from 100 percent mulberry silk—soft, breathable, and gentle on skin and hair. It blocks out light without feeling heavy, keeping you comfortable even on long-haul flights. Plus, the adjustable strap ensures a snug fit without leaving marks, so you can land looking (and feeling) more rested than anyone else on the plane.
Rorry Portable Wireless Charger
Amazon
Save yourself the trouble of a dead phone with this compact Rorry portable charger, which plugs directly into your phone—no cables needed. Despite its keychain size, it packs a serious punch with 5000mAh of power, enough to fully recharge most smartphones at least once. It also supports fast charging and can double as a wireless power bank for compatible devices, making it a sleek, travel-friendly essential you’ll never regret packing.
Bose QuietComfort Noise Cancelling Headphones
Amazon
There’s a baby screaming in 44F, your neighbor snores, and you need to sleep before your meeting in the morning. Noise-cancelling headphones are your only hope—and Bose remains the gold standard. The QuietComfort model delivers world-class active noise cancellation with multiple modes so you can adjust how much of the cabin noise you let in. They’re lightweight, incredibly comfortable for long wear, and have up to 24 hours of battery life on a single charge. Whether you’re tuning into a podcast, drifting off to white noise, or just craving silence, these are a sanity-saving must for any frequent flyer.
Pavilia Travel Blanket
Amazon
Being hot on a plane is a nightmare, but being cold on a plane? (Like, teeth-chattering cold?) is worse. That’s why this travel blanket from Pavilia is such a smart pick: it measures about 65 inches by 40 inches, offering plenty of cozy coverage without feeling bulky. Made of soft microfleece polyester, it’s lightweight yet warm, folding down neatly into a compact carry case that can double as a pillow when packed. It also features a luggage sleeve and strap so you can easily clip it to your suitcase or backpack, and armholes that let you move comfortably without losing warmth.
Gowraps Luggage Handle Wraps Set
Amazon
I’ve heard too many intercom announcements asking a passenger to come back to gate 57 as they grabbed the wrong carry-on from the overhead bin. Particularly if you have a popular brand of suitcase, these luggage handle wraps will be your saving grace. Made from durable neoprene and secured with Velcro, they not only cushion your grip for more comfortable carrying but also make your bag instantly recognizable. Each set comes with five brightly colored wraps—so you can easily spot your luggage in an overhead bin or carousel lineup, and even color-code for family members or multiple bags.
Curad Alcohol Prep Pads
Amazon
Alcohol wipes are cheap and good to have on hand for two things: to prep a cut or wound before applying a bandage, and also because the sharp, sterile scent of alcohol can actually help ease nausea. Ideal for those moments when your flight hits rough turbulence or an unexpected go-around, these individually wrapped Curad wipes are compact, TSA-friendly, and easy to stash in a pocket or toiletry kit. Each box includes 100 swabs, so you’ll have plenty to last through multiple trips (and a few queasy travel companions).
Airplane Pockets Seat Storage Organizer
Amazon
Nightmare fuel: You get to your seat only to realize the seat-back pocket is about an inch deep with no real space for your water bottle or even your wallet (and yes, you do want to buy that snack later). Not only that, but you’re in a window seat, and your bag is hard to reach without knocking your neighbour. This organizer solves all that. It slips over the tray table and/or seat-back and gives you four expandable pockets—perfect for stashing your phone, tablet, snacks, water bottle, and travel documents where you can actually get to them. Made of durable, machine-washable material, it not only expands your storage but also gives you a cleaner surface to work or eat on.
Lysol Travel Disinfectant Spray Pack of 4
Amazon
Compact but powerful, this set of travel-sized Lysol spray is a frequent flyer essential. It kills 99.9 percent of germs and bacteria on hard and soft surfaces alike—perfect for misting over your seat, headrest, or hotel remote once you land. Each 1-ounce bottle is TSA-compliant, making it easy to toss into your quart-size bag and pull out whenever you want a little extra peace of mind (and freshness) while flying.
Loop Quiet 2 Earplugs
Amazon
I love my Loop earplugs because they’re discreet, reusable, and incredibly effective at dulling ambient noise without blocking it completely—you’ll still hear announcements, but that crying baby or loud seatmate? Blissfully muted. Made with soft silicone for all-night comfort, they come in multiple sizes and a compact carrying case, making them just as useful for flights as they are for concerts, festivals, or any noisy setting where you want to tune out, not zone out.
Cura-heat Heat Therapy Patches
Amazon
Cura-heat patches are always in my personal item. Whether it’s a cramped seat, an awkward sleeping position, or just hours of sitting still, these therapy patches are a game-changer. Air-activated and designed to stick to your clothing (not your skin), they deliver up to 12 hours of gentle, steady warmth to relieve sore muscles, period cramps, or tension in your neck and shoulders. Slip one on after takeoff and let the soothing heat work its magic—so you land feeling relaxed instead of knotted up.
Thinx Period Underwear
Amazon
This is one of those things you won’t know how you ever flew without. If you’ve just had a baby, are expecting your period, or deal with irregular cycles, period underwear offers peace of mind for whatever might arise mid-flight. Thinx’s breathable, leakproof design absorbs up to five regular tampons’ worth, keeping you comfortable and protected without the need to rush to the bathroom midair when the seatbelt sign is on and flight attendants are frazzled. Perfect for long-haul flights where changing clothes is a full operation, these are a discreet, dependable travel essential that makes your journey infinitely less stressful.
Welly First Aid Kit
Amazon
Being prepared for even minor mishaps makes a huge difference when you’re thousands of feet in the air—and that’s exactly where this handy emergency tin comes in. Compact yet surprisingly comprehensive, the Welly kit includes flexible fabric bandages, waterproof options, non-stick pads, tape, cleansing wipes, and single-use antibiotic ointments. It fits easily in your carry-on or seat pocket, so whether you nick your finger opening a snack, get a blister from airport sprints, or just want peace of mind mid-flight, this little kit has you covered.
Fyy Daily Pill Organizer
Amazon
It is so, so, so important to have emergency meds on you when traveling—especially on a plane. Stock a little guy like this compact pill organizer with essentials like Pepto Bismol, Tylenol, Zinc, and a sleeping aid to help you conk out mid-flight. This organizer features eight secure compartments to keep everything organized and spill-proof, plus a sleek, palm-sized design that easily fits in a toiletry bag or pocket. It’s lightweight, durable, and makes it easy to handle anything from headaches to heartburn without rummaging through your entire carry-on.
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